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What is the cheapest statin drug? The most expensive statin per 30 tablets was atorvastatin with a mean price of $21.48, and the least expensive statin was simvastatin with a mean price of $5.89.
What medications should not be taken with statins? But there are some drug combinations that should be avoided, the heart association warns. Lovastatin (Mevacor), simvastatin (Zocor) and pravastatin (Pravachol) should not be used with the fibrate cholesterol drug gemfibrozil, for example, because of the risk of muscle injury.
Why do you have to take simvastatin at bedtime? They act by inhibiting the enzyme HMG CoA reductase, which controls synthesis of cholesterol in the liver. Most manufacturers of statins recommend that they are taken at night, on the basis of physiological studies which show that most cholesterol is synthesised when dietary intake is at its lowest.
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